Tag: M.W:300-400

Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, get their minds active, and encourage them to do something that doesn’t involve a screen. 10343-06-3, C14H20O10. A document type is Article, introducing its new discovery., Computed Properties of C14H20O10

Synthesis, gp120 binding and anti-HIV activity of fatty acid esters of 1,1-linked disaccharides

Inspired by the anti-human immunodeficiency virus (HIV) activity of analogues of beta-galactosylceramide (GalCer), a set of mono- and di-saccharide fatty acid esters were designed as GalCer mimetics and their binding to the V3 loop peptide of HIV-1 and anti-HIV activity evaluated. 1,1-linked Gal-Man and Glu-Man disaccharides with an ester on the Man subunit bound the V3 loop peptide and inhibited HIV infectivity in single round infection assays with the TZM-bl cell line. IC50’s were in the 50 muM range with no toxicity to the cells at concentrations up to 200 muM. These compounds appear to inhibit virus entry at early steps in viral infection since they were inactive if added post viral entry. Although these compounds were found to bind to the V3 loop peptide of gp120, it is not clear that this interaction is responsible for their anti-HIV activity because the relative binding affinity of closely related analogues did not correlate with their antiviral behavior. The low cytotoxicity of these 1,1-linked disaccharide fatty acid esters, combined with the easy accessibility to structurally diverse analogues make these molecules attractive leads for new topical anti-viral agents.

Interested yet? Keep reading other articles of 10343-06-3!, Computed Properties of C14H20O10

Reference：
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

In an article, published in an article, once mentioned the application of 951127-25-6, Name is tert-Butyl ((2R,3S)-2-(2,5-difluorophenyl)-5-oxotetrahydro-2H-pyran-3-yl)carbamate,molecular formula is C16H19F2NO4, is a conventional compound. this article was the specific content is as follows.Recommanded Product: 951127-25-6

Pyran derivative salt or its salt hydrate and its preparation and use (by machine translation)

The invention relates to a benzopyran derivative salt or its salt hydrate and its preparation and application, and in particular relates to dipeptide kinase – IV inhibitor a pharmaceutically acceptable salt or its salt hydrate, and its preparation method and application, further for the purposes of formula (I) as shown in the salt or its salt hydrate and its preparation method and application. (by machine translation)

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Reference：
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 499-40-1, Name is (2R,3S,4R,5R)-2,3,4,5-Tetrahydroxy-6-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexanal, molecular formula is C12H22O11. In a Article，once mentioned of 499-40-1, HPLC of Formula: C12H22O11

Group-13 metal-induced coordination variation of the Bis(2-pyridyl)amide ligand in solution and in the solid state

Ligands containing aromatic nitrogen heterocycles play a leading role in the molecular self assembling processes that lead to macromolecular architectures. The inductive effect of various metal fragments on those building blocks has not yet been studied systematically. To evaluate this effect we synthesized the homologous series of Group-13 metal complexes [Me2AlPy2N] (1), [Me2GaPy2N] (2), [Me2InNPy2]2 (3), and [Me2TlNPy2]x (4) (Py = 2-NC5H4), and characterized them by low-temperature X-ray structure analysis and 15N-NMR spectroscopy in solution. The electronic equivalence of the central and the ring nitrogen atoms leaves the energetic hyperface of the anion quite flat, and the electron density is polarized according to the requirements of the metal. In the aluminum and the gallium complexes 1 and 2 the metal center is coordinated exclusively through the nitrogen atoms within the pyridyl rings. The complexes with these hard metals are close-contact ion pairs. In the indium complex 3 the ciscis orientation gives rise to a dimeric structure, while the unprecedented cis-trans arrangement in the thallium compound 4 leads to a polymeric structure. The complexes 3 and 4 have to be regarded as separated ion pairs of Me2M+ cations and Py2N- anions without any covalent bonds between the anionic moiety and the dimethylmetal cations, even in the solid state. The series of complexes proves the bis(2-pyridyl)amide to be an excellent self-adapting ligand. These findings are substantiated by NMR-spectroscopic studies in solution. Not only do the steric requirements of N heteroaromatic ligands have to be considered in molecular self-assembling processes but also the inductive effect of the different metal fragments.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.HPLC of Formula: C12H22O11. In my other articles, you can also check out more blogs about 499-40-1

Reference：
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.499-40-1, Name is (2R,3S,4R,5R)-2,3,4,5-Tetrahydroxy-6-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexanal, molecular formula is C12H22O11. In a Patent，once mentioned of 499-40-1, Quality Control of: (2R,3S,4R,5R)-2,3,4,5-Tetrahydroxy-6-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexanal

COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND A ELECTRONIC DEVICE THEREOF

The present invention refers to organic electroluminescence device request is characteristic of low voltage driving and 22g, to implement high efficiency element, bis indole derivative compounds through the development low voltage driving and high name, high efficiency core layer are disclosed. (by machine translation)

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Quality Control of: (2R,3S,4R,5R)-2,3,4,5-Tetrahydroxy-6-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexanal, you can also check out more blogs about499-40-1

Reference：
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 10343-06-3, Name is 2,3,4,6-Tetra-o-acetyl-D-glucopyranose, HPLC of Formula: C14H20O10.

Catechin Glucosides: Occurrence, synthesis, and stability

Catechins are flavonoids with suggested health benefits, but are unstable during storage, processing and, after ingestion, during gut transit. We hypothesized that catechin glucosidos, which occur in various plants, could be more stable than unsubstituted catechin, and additionally be deglucosylated in the gut and so act to deliver catechin in a form able to be absorbed. (+)-Catechin O-glucosides from various sources have been used in the course of this investigation. (+)-Catechin 3′-O-beta-D-glucopyranoside (C3’G), (+)-catechin 5-O-beta-D-glucopyranoside (C5G), and (+)-catechin 3-O-beta-D-glucopyranoside (C3G) were chemically synthesized. (+)-Catechin 4′-O-beta-D-glucopyranoside (C4’G) and (+)-catechin 7-O-beta-D-glucopyranoside (C7G) were prepared enzymically using preparations from lentil and barley. In general, but with some exceptions, the (+)-catechin glucosidos were more stable between pH 4 and 8 than (+)-catechin, with C3’G exhibiting greatest stability. The intestinal metabolism of (+)-catechin and all (+)-catechin glucosides in the gut was determined by perfusion of rat intestine in vivo. C3’G and C5G were extensively deglycosylated in the gut, and C3’G showed greatest apparent “absorption” as calculated by the difference between effluent and influent. The results show the potential of catechin glucosides, especially C3’G, as more stable prescursors of catechin.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.HPLC of Formula: C14H20O10. In my other articles, you can also check out more blogs about 10343-06-3

Reference：
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.10034-20-5, Name is (2S,3R,4R,5S,6R)-6-(Acetoxymethyl)-3-aminotetrahydro-2H-pyran-2,4,5-triyl triacetate hydrochloride, molecular formula is C14H22ClNO9. In a Patent，once mentioned of 10034-20-5, Recommanded Product: (2S,3R,4R,5S,6R)-6-(Acetoxymethyl)-3-aminotetrahydro-2H-pyran-2,4,5-triyl triacetate hydrochloride

SELECTIVE GLYCOSIDASE INHIBITORS AND USES THEREOF

The invention provides compounds with enhanced permeability for selectively inhibiting glycosidases, prodrugs of the compounds, and pharmaceutical compositions including the compounds or prodrugs of the compounds. The invention also provides methods of treating diseases and disorders related to deficiency or overexpression of O-GlcNAcase, accumulation or deficiency of O-GlcNAc

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Recommanded Product: (2S,3R,4R,5S,6R)-6-(Acetoxymethyl)-3-aminotetrahydro-2H-pyran-2,4,5-triyl triacetate hydrochloride, you can also check out more blogs about10034-20-5

Reference：
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 10343-06-3, Name is 2,3,4,6-Tetra-o-acetyl-D-glucopyranose, molecular formula is C14H20O10. In a Article，once mentioned of 10343-06-3, Recommanded Product: 2,3,4,6-Tetra-o-acetyl-D-glucopyranose

Ab initio analysis of the interaction of CO2 with acetylated d -glucopyranose derivatives

Peracetylated d-glucopyranose has a high solubility in CO2 and can be a promising phase-change physical solvent or absorbent for CO2, as reported recently. However, peracetylated d-glucopyranose is unstable under acidic atmospheres, especially in sulfur-containing waste gases, and the possibly major decomposition products are 2,3,4,6-tetra-O-acetyl-d-glucopyranose, 1-thiol-d-glucopyranose tetraacetate, and 1-mercaptoethyl-d-glucopyranose tetraacetate. Therefore, it is highly interesting to investigate the interaction between CO2 and these three compounds using ab initio calculations, including geometry optimizations with HF/3-21G, B3LYP/6-31+G??and single-point energy calibration with MP2/aug-cc-pVDZ. The results indicate that the electrostatic interactions between the substrates and CO2 are mainly influenced by the interaction distance and the numbers of negative charge donors or the interacting pairs involved in the complex. It is furthermore found that DeltaE increases significantly if S and O atoms could interact with CO2 simultaneously. The binding energy is irrelevant if one considers the chemical environment of the O atom (i.e. OAc, OE or OS) or the S atom (i.e. SEt or SH), and the electronegativity difference between the S and O atoms. The three substrates studied are still excellent CO2-philes, although their average DeltaE (-20kJ/mol) is slightly lower than that of peracetylated d-glucose (-22kJ/mol), which has one more O atom that can interact with CO2. Therefore, the applications of carbohydrates can be expanded to include adsorbents for CO2, SO2 or both, and the functional groups attached to the carbohydrate can vary from those to the acetyl groups.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Recommanded Product: 2,3,4,6-Tetra-o-acetyl-D-glucopyranose. In my other articles, you can also check out more blogs about 10343-06-3

Reference：
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.499-40-1, Name is (2R,3S,4R,5R)-2,3,4,5-Tetrahydroxy-6-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexanal, molecular formula is C12H22O11. In a Article，once mentioned of 499-40-1, Product Details of 499-40-1

Adipate as a tetradentate bridging ligand: Synthesis, structure and properties of Cu(II) and Ni(II) compounds with 2,2?-dipyridylamine as a terminal co-ligand

The synthesis, characterization, single crystal structures and physical properties of the compounds [Cu2(dpa)2(adp) 2](H2O)2 (1) and [Ni2(dpa) 2(adp)]Cl2 (2), in which dpa = 2,2?-dipyridylamine; adp = adipate(2-) anion, are presented. In both dinuclear compounds the dpa is chelating bidentately, whereas adipate acts as a tetradentate bridge between the 2 metal ions, using both carboxylate oxygen atoms as a chelate. The Cu(II) compound has 2 bridging adipate dianions, whereas the Ni(II) compound has a single bridging adipate(2-); in the latter case the charge of the dinuclear unit is compensated by 2 lattice chloride anions. The N-H of the dpa donates an intermolecular H bond to neighboring molecules; i.e. to the carboxylates for the Cu compound and to the lattice chlorides for the Ni one. In both compounds the metal ions are in a distorted octahedral geometry, and diffuse reflectance spectra agree with this geometry. The Ni?Ni contact distance is very long (1089.3 pm). The EPR spectrum of the Cu(II) compound shows a broad signal, and no hyperfine signals are resolved; also no spin = 1 signals are seen, which is in agreement with the very long dinuclear Cu?Cu contact distance (831.7 pm). Magnetic susceptibility measurements of the Cu compound down to 5 K show a very weak ferromagnetic coupling with a magnetic moment (per Cu) increasing from 1.73 B.M. (room T) to 1.88 B.M. (at 5 K).

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Product Details of 499-40-1, you can also check out more blogs about499-40-1

Reference：
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

In an article, published in an article, once mentioned the application of 951127-25-6, Name is tert-Butyl ((2R,3S)-2-(2,5-difluorophenyl)-5-oxotetrahydro-2H-pyran-3-yl)carbamate,molecular formula is C16H19F2NO4, is a conventional compound. this article was the specific content is as follows.Recommanded Product: tert-Butyl ((2R,3S)-2-(2,5-difluorophenyl)-5-oxotetrahydro-2H-pyran-3-yl)carbamate

Aryl substituted amino hydrogen pyrane class compound and use thereof (by machine translation)

The invention relates to an aryl substituted amino hydrogen pyrane class compounds and their use, further relates to the pharmaceutical composition. The compound of the invention or the pharmaceutical composition can be used as dipeptidyl peptidase – IV (DPP – IV) inhibitors. (by machine translation)

Do you like my blog? If you like, you can also browse other articles about this kind. Recommanded Product: tert-Butyl ((2R,3S)-2-(2,5-difluorophenyl)-5-oxotetrahydro-2H-pyran-3-yl)carbamate. Thanks for taking the time to read the blog about 951127-25-6

Reference：
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 10343-06-3, Name is 2,3,4,6-Tetra-o-acetyl-D-glucopyranose, molecular formula is C14H20O10. In a Article，once mentioned of 10343-06-3, Quality Control of: 2,3,4,6-Tetra-o-acetyl-D-glucopyranose

Synthesis and use of glycosyl phosphites: An effective route to glycosyl phosphates, sugar nucleotides, and glycosides

An efficient and convenient synthetic route to glycosyl phosphites and phosphates has been developed that uses dibenzyl N,N-diethylphosphoramidite as a phosphitylating reagent. Glycosyl phosphites and phosphates of 2-acetamido-2-deoxy-D-galactose (GalNAc) (29), 2-acetamido-2-deoxy-D-glucose (GlcNAc) (30), D-galactose (Gal) (31), D-glucose (Glc) (32), D-mannose (Man) (33), L-rhamnose (Rha) (34), L-fucose (Fuc) (35), and N-acetylneuraminic acid (NeuAc) (41) were prepared by this procedure. Compounds 29 and 30 were obtained as alpha anomers exclusively, whereas compounds 31, 32, and 41 were obtained as beta anomers, and compounds 33 and 34, as alpha anomers, predominately. The phosphates are useful for the synthesis of sugar nucleotides, and the phosphites are effective glycosylation reagents.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Quality Control of: 2,3,4,6-Tetra-o-acetyl-D-glucopyranose. In my other articles, you can also check out more blogs about 10343-06-3

Reference：
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics