951127-25-6, tert-Butyl ((2R,3S)-2-(2,5-difluorophenyl)-5-oxotetrahydro-2H-pyran-3-yl)carbamate is a Tetrahydropyrans compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
951127-25-6, At room temperature, 6a(0.327 g, 1.10 mmol) was dissolved in Nu, Nu-dimethylacetamide(4 mL) was added intermediate 1 (0.356 g, 1.10 mmol) and stirred at 0 C for 1 hour. Sodium tris (acetoxy) borohydride (0.303 g, 1.43 mmol) was added to the reaction solution and allowed to warm to room temperature for 16 hours. The reaction solution was cooled to C, followed by adding water and aqueous ammonia to adjust the pH to 8 to precipitate a white solid. The filter cake was washed successively with water (5 mL chi 3) and petroleum ether (10 mL chi 1). The residue was dried and the cake was dried to give a white solid 6b (0.367 g, 63.7% yield).
951127-25-6 tert-Butyl ((2R,3S)-2-(2,5-difluorophenyl)-5-oxotetrahydro-2H-pyran-3-yl)carbamate 44193925, aTetrahydropyrans compound, is more and more widely used in various fields.
Reference£º
Patent; SICHUAN HAISCO PHARMACEUTICAL CO., LTD; FAN, JIANG; FENG, JIAN-CHUAN; PENG, FEI; CHEN, QING-PING; (89 pag.)TW2017/8224; (2017); A;,
Tetrahydropyran – Wikipedia
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